Knowing Ourselves

Knowing ourselves: A theoretical model of culture

Education has been viewed as a process of enculturation into the beliefs, practices, values and styles of discourse of a particular community. Recognition and awareness of an institution’s particular cultural values and norms can be a useful tool to guide actions and reactions to change. A model is proposed to guide a cultural analysis, at the institutional or disciplinary level, based on Schei...

Ourselves

Irradiating Ourselves

Background: Efficient incorporation of the cellular cytidine deaminase APOBEC3G (APO3G) into HIV-1 virions is necessary for its antiviral activity. Even though cellular RNAs are known to be nonspecifically incorporated into virus particles, we have previously found that encapsidation of APO3G into HIV-1 virions is specifically enhanced by viral genomic RNA. Intracellularly, APO3G was found to f...

Protect Us from Ourselves

Exposing ourselves to art.

Background: Apolipoprotein B-100 (apo B-100) stands as one of the largest proteins in humans. Its large size of 4536 amino acids hampers the production of X-ray diffraction quality crystals and hinders in-solution NMR analysis, and thus necessitates a domain-based approach for the structural characterization of the multi-domain full-length apo B. Results: The structure of apo B-17 (the N-termin...